Adherence to the preventive strategies for nonsteroidal anti-inflammatory drug- or low-dose aspirin-induced gastrointestinal injuries

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Initial Steps to Prevent Nonsteroidal Anti-Inflammatory Drug- or Aspirin-Induced Enteropathy: Long-Term Outcome Data

Nonsteroidal anti-inflammatory drugs (NSAIDs) and lowdose aspirin are among the most frequently prescribed and used medications. With the development of video capsule endoscopy, the frequency and severity of NSAID enteropathy has become more evident. NSAID-induced enteropathy has a different pathological mechanism from gastroduodenal mucosal injury, so different treatments and preventative stra...

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Nonsteroidal Anti-inflammatory Drug-related Gastrointestinal Bleeding in the Elderly

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Low-dose Aspirin, Nonsteroidal Anti-inflammatory Drugs, Selective COX-2 Inhibitors and Breast Cancer Recurrence.

BACKGROUND Aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and selective COX-2 inhibitors may improve outcomes in breast cancer patients. We investigated the association of aspirin, NSAIDs, and use of selective COX-2 inhibitors with breast cancer recurrence. METHODS We identified incident stage I-III Danish breast cancer patients in the Danish Breast Cancer Cooperative Group registry,...

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Utilization of gastroprotective strategies for nonsteroidal anti-inflammatory drug-induced gastrointestinal events in a major teaching hospital

BACKGROUND AND PURPOSE Clinical guidelines recommend the prescribing of gastroprotective strategies in nonsteroidal anti-inflammatory drug (NSAID) users with risk factors for gastrointestinal (GI) ulcer or ulcer complications. However, these guidelines are not often translated into clinical practice. Therefore, the aim of this study was to investigate the utilization of gastroprotective strateg...

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BACKGROUND Gastroprotective agents are recommended for patients receiving low-dose aspirin (LDA) or nonsteroidal anti-inflammatory drugs (NSAIDs). Vonoprazan is a potassium-competitive acid blocker recently approved for the prevention of peptic ulcer recurrence in patients receiving LDA or NSAIDs. METHODS This phase 2, open-label, single-center study in healthy Japanese males evaluated drug-d...

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ژورنال

عنوان ژورنال: Journal of Gastroenterology

سال: 2013

ISSN: 0944-1174,1435-5922

DOI: 10.1007/s00535-013-0771-8